This is admittedly a very, very niche setup.

Some things I did, not sure which are necessary:

1. Install tmux: brew install tmux.
2. Install tpm (tmux plugin manager) from GitHub. (Followed instructions there.)
3. Install Powerline fonts GitHub. Followed instructions, basically executing ./install.sh at the terminal.
4. Install the powerline-status package into my Anaconda base directory. pip install powerline-status.
5. Set Hyper's font family (Cmd-,) in a text editor:

    // font family with optional fallbacks
    fontFamily: '"Terminess Powerline", "Anonymice Powerline", "Roboto Mono for Powerline", "Meslo LG S for Powerline", "DejaVu Sans Mono", "Lucida Console", monospace',

As well as the plugins:

    plugins: [
      'nord-hyper',
    ],

1. Create new Hyper window. (The settings are applied directly).

I think that is it.